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Is Tretinoin safe during pregnancy?

Prescription retinoid. Generally avoided in pregnancy; low risk while breastfeeding if kept off the breast.

PregnancyNot recommended
BreastfeedingUse with care
EvidenceModerate

What the sources say

ACOG and AAD recommend stopping topical tretinoin during pregnancy. MotherToBaby notes that studies have not found more birth defects with proper skin use and little is absorbed, but avoiding it in pregnancy is still the usual advice; absorption rises on broken skin or large areas. LactMed: not studied in breastfeeding, but poorly absorbed and considered low risk. Do not apply to the nipple/areola and avoid baby skin contact with treated areas.

Common alternatives

Also listed as

all-trans retinoic acid, altreno, atra, atralin, avita, refissa, renova, retin a, retin-a, retinoic acid, veltin, vitamin a acid

Sources

Last reviewed . This is general information, not medical advice. Ask your doctor or midwife about your own situation.

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