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Is Azelaic Acid safe during pregnancy?

A go-to pregnancy-safe option for acne, redness and dark spots, per ACOG and AAD.

PregnancyGenerally safe
BreastfeedingGenerally safe
EvidenceModerate

What the sources say

ACOG lists azelaic acid among OTC acne ingredients that can be used in pregnancy, and AAD says it is thought to be safe (no birth defects in animal studies). LactMed: only about 4% is absorbed and it occurs naturally in foods and breast milk, so it is low risk while breastfeeding; avoid applying it to the nipple and keep treated skin away from the baby. Derivatives like potassium azeloyl diglycinate have not been studied separately.

Also listed as

azelex, azeloglycine, finacea, nonanedioic acid, potassium azeloyl diglycinate

Sources

Last reviewed . This is general information, not medical advice. Ask your doctor or midwife about your own situation.