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Is Methylisothiazolinone safe during pregnancy?

Preservative mainly in rinse-off products and wipes. No pregnancy concern identified; the main issue is skin allergy.

PregnancyUse with care
BreastfeedingUse with care
EvidenceLimited

What the sources say

Reviews describe methylisothiazolinone (MI) as a common cause of preservative contact allergy, mostly from rinse-off cosmetics, wipes and household products. No sources raise pregnancy- or breastfeeding-specific concerns, but no pregnancy studies exist. Limit: fine in rinse-off products for most people; if you get an itchy rash, look for MI-free products. Pregnancy can make skin more sensitive.

Also listed as

2-methyl-4-isothiazolin-3-one, neolone 950

Sources

Last reviewed . This is general information, not medical advice. Ask your doctor or midwife about your own situation.

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